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A white woman with blonde-brown hair and green eyes. She is wearing a v neck pink sweater and smiling with her front teeth showing.

Caitlin Kilgore

Updated: 03/24/2022

Hopefully you got the memo that gut health is a key component to overall health. The trillions of microorganisms living in your gut play a major role in everything from digestion to immunity to cognition — and can even impact your emotions. (Fun fact: A large amount of your serotonin is produced in the gut).

But did you know that certain strains of bacteria can actually influence your ability to shed unhealthy — unwanted — pounds? “When your microbiome is out of whack, it's almost impossible to lose weight,” says Jordan Crofton, FNP, Director of Patient Care at THE WELL.

Research continues to demonstrate that the composition of gut bacteria in your system can either help or hinder your ability to move the needle on the scale. How do these microscopic germs have such sway?

RELATED: 6 Ways an Out-of-Balance Gut Affects Your Well-Being

In one recent study, researchers found that genes within these bacteria can influence the rate at which bacteria grows, the effectiveness of nutrient absorption from food and whether certain nutrients (like fiber and starches) get broken down into sugars in a way that can impact weight loss.

“We've identified specific genetic signatures in the gut microbiome that were predictive of weight loss response in a small cohort of patients following a healthy lifestyle intervention," study author Sean Gibbons, PhD, told WebMD.

“In our study, we found that some of the fastest-growing microbes in the weight-loss responder group were from the genus Prevotella,” says Gibbons.

On the flip side, Gibbons and his team also found some strains of bacteria are linked to weight loss resistance — specifically, the bacteria that produce an increase in enzymes needed to turn starches and fibers into sugar.

Crofton agrees, noting specific bacterial strains that can be particularly problematic:

“Two bacterial phyla called Bacteroidetes and Firmicutes dominate the human digestive tract, and analyses have found that high Firmicutes and low Bacteroidetes (resulting in a high F/B ratio) is a microbial imbalance that can lead to weight gain, inflammation and impaired insulin sensitivity,” explains Crofton.

Research also shows us that there are decreased levels of Akkermansia muciniphila (one of the most abundant beneficial microbes in the human microbiome) in patients struggling with obesity and metabolic syndrome,” says Crofton, adding that these levels are one of the things she makes sure to evaluate for in her patients.


How to Give Your Gut Much-Needed Support

It’s not impossible to figure out the exact composition of bacteria living in your gut (thanks, gut microbiome testing!). But it’s also not super easy — especially if you don’t have access to a functional medicine provider.

Luckily, one of the best ways to kick your gut microbiome into high gear is a cleanse — and it’s something you can do on your own.

That said, not every cleanse is created equal. “There are a lot of different detoxes and cleanses on the market right now and many can do more harm than good,” says Crofton. THE WELL Cleanse, however, is a science-backed, doctor-designed food-forward protocol that resets your system by targeting the gut microbiome while allowing you to eat healing, nutrient-dense foods, explains Crofton, who adds: “We developed a blend of herbal antimicrobials, digestive enzymes and detoxification support, which specifically address gut dysbiosis and support the body's ability to detoxify.”

These supplements “provide immediate benefits like easing digestive issues and supporting immune function,” says Lauren Burkowski, THE WELL Health Coach. Plus, the dietary guidelines are sustainable (you get to eat real food!) and set you up for long-term health — including weight loss and management, healthy skin, improved digestion and more.

RELATED: I Tried THE WELL Cleanse, Here’s What Happened

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